Edited magnetic resonance spectroscopy detects an age-related decline in monkey brain GABA levels
نویسنده
چکیده
....................................................................................................................... v LIST OF TABLES ............................................................................................................. ix LIST OF FIGURES ............................................................................................................ x INTRODUCTION .............................................................................................................. 1 Purpose of this study ....................................................................................................... 1 Background ..................................................................................................................... 1 Magnetic resonance spectroscopy Basics ....................................................................... 2 GABA detection using MEGA-PRESS .......................................................................... 4 METHODS ......................................................................................................................... 6 The workflow chart ......................................................................................................... 6 Subjects ........................................................................................................................... 7 MRI and MRS acquisition............................................................................................... 7 MRS setting ..................................................................................................................... 7 The VOI localization ....................................................................................................... 8
منابع مشابه
Edited magnetic resonance spectroscopy detects an age-related decline in brain GABA levels
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the brain. Although measurements of GABA levels in vivo in the human brain using edited proton magnetic resonance spectroscopy ((1)H-MRS) have been established for some time, it is has not been established how regional GABA levels vary with age in the normal human brain. In this study, 49 healthy men and 51 healthy wom...
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